| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM83475 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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| EC50 | >99000±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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|
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| BDBM83475 |
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| n/a |
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| Name | BDBM83475 |
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| Synonyms: | 2-(9-methoxy-6-indolo[3,2-b]quinoxalinyl)acetic acid methyl ester | 2-(9-methoxyindolo[3,2-b]quinoxalin-6-yl)acetic acid methyl ester | MLS000040504 | SMR000043436 | cid_662646 | methyl 2-(9-methoxyindolo[3,2-b]quinoxalin-6-yl)acetate | methyl 2-(9-methoxyindolo[3,2-b]quinoxalin-6-yl)ethanoate |
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| Type | Small organic molecule |
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| Emp. Form. | C18H15N3O3 |
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| Mol. Mass. | 321.33 |
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| SMILES | COC(=O)Cn1c2ccc(OC)cc2c2nc3ccccc3nc12 |
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| Structure | 
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