| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
|---|
| Ligand | BDBM83483 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
|---|
| EC50 | >99000±n/a nM |
|---|
| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Endoribonuclease toxin MazF |
|---|
| Name: | Endoribonuclease toxin MazF |
|---|
| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 12100.43 |
|---|
| Organism: | Escherichia coli str. K-12 substr. MG1655 |
|---|
| Description: | gi_16130689 |
|---|
| Residue: | 111 |
|---|
| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
|
|
|
|---|
| BDBM83483 |
|---|
| n/a |
|---|
| Name | BDBM83483 |
|---|
| Synonyms: | 1'-acetyl-4,7-dibutoxy-1,3-dihydrospiro[benzimidazole-2,3'-indol]-2'(1'H)-one | 1'-acetyl-4,7-dibutoxy-2'-spiro[1,3-dihydrobenzimidazole-2,3'-indole]one | 1'-acetyl-4,7-dibutoxy-spiro[1,3-dihydrobenzimidazole-2,3'-indoline]-2'-one | 1'-acetyl-4,7-dibutoxyspiro[1,3-dihydrobenzimidazole-2,3'-indole]-2'-one | 4,7-dibutoxy-1'-ethanoyl-spiro[1,3-dihydrobenzimidazole-2,3'-indole]-2'-one | MLS000084636 | SMR000018984 | cid_3239485 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H29N3O4 |
|---|
| Mol. Mass. | 423.5048 |
|---|
| SMILES | CCCCOc1ccc(OCCCC)c2NC3(Nc12)C(=O)N(C(C)=O)c1ccccc31 |
|---|
| Structure | 
|
|---|
Search and Browse
