Reaction Details |
| Report a problem with these data |
Target | Endoribonuclease toxin MazF |
---|
Ligand | BDBM83492 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
---|
EC50 | 9320±n/a nM |
---|
Citation | PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Endoribonuclease toxin MazF |
---|
Name: | Endoribonuclease toxin MazF |
Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 12100.43 |
Organism: | Escherichia coli str. K-12 substr. MG1655 |
Description: | gi_16130689 |
Residue: | 111 |
Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
|
|
|
BDBM83492 |
---|
n/a |
---|
Name | BDBM83492 |
Synonyms: | (3-Cyano-6-methyl-quinolin-2-ylsulfanyl)-acetic acid ethyl ester | 2-[(3-cyano-6-methyl-2-quinolinyl)thio]acetic acid ethyl ester | 2-[(3-cyano-6-methyl-2-quinolyl)thio]acetic acid ethyl ester | MLS000526005 | SMR000116479 | cid_865641 | ethyl 2-(3-cyano-6-methyl-quinolin-2-yl)sulfanylethanoate | ethyl 2-(3-cyano-6-methylquinolin-2-yl)sulfanylacetate |
Type | Small organic molecule |
Emp. Form. | C15H14N2O2S |
Mol. Mass. | 286.349 |
SMILES | CCOC(=O)CSc1nc2ccc(C)cc2cc1C#N |
Structure |
|