| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM83587 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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| EC50 | 5590±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM83587 |
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| n/a |
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| Name | BDBM83587 |
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| Synonyms: | (5-amino-1-methylsulfonylpyrazol-3-yl) 2-methyl-3-nitrobenzoate | (5-azanyl-1-methylsulfonyl-pyrazol-3-yl) 2-methyl-3-nitro-benzoate | 2-methyl-3-nitro-benzoic acid (5-amino-1-mesyl-pyrazol-3-yl) ester | 2-methyl-3-nitrobenzoic acid (5-amino-1-methylsulfonyl-3-pyrazolyl) ester | MLS000680202 | SMR000324479 | cid_4461783 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H12N4O6S |
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| Mol. Mass. | 340.312 |
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| SMILES | Cc1c(cccc1[N+]([O-])=O)C(=O)Oc1cc(N)n(n1)S(C)(=O)=O |
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| Structure | 
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