Reaction Details |
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Target | Endoribonuclease toxin MazF |
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Ligand | BDBM83606 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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EC50 | 11000±n/a nM |
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Citation | PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Endoribonuclease toxin MazF |
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Name: | Endoribonuclease toxin MazF |
Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 12100.43 |
Organism: | Escherichia coli str. K-12 substr. MG1655 |
Description: | gi_16130689 |
Residue: | 111 |
Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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BDBM83606 |
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n/a |
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Name | BDBM83606 |
Synonyms: | 5-[(2Z)-2-(2,2-dimethyl-6-phenyl-1,3-dioxin-4-ylidene)ethylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione | 5-[(2Z)-2-(2,2-dimethyl-6-phenyl-1,3-dioxin-4-ylidene)ethylidene]-2-thioxo-hexahydropyrimidine-4,6-quinone | MLS000711190 | SMR000280957 | cid_1617287 |
Type | Small organic molecule |
Emp. Form. | C18H16N2O4S |
Mol. Mass. | 356.396 |
SMILES | [#6]C1([#6])[#8]\[#6](=[#6]/[#6]=[#6]-2/[#6](=O)-[#7]-[#6](=S)-[#7]-[#6]-2=O)-[#6]=[#6](-[#8]1)-c1ccccc1 |c:17| |
Structure |
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