| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM83666 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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| EC50 | 5260±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM83666 |
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| n/a |
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| Name | BDBM83666 |
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| Synonyms: | 4-methylbenzoic acid [5-amino-1-(4-fluorophenyl)sulfonyl-3-pyrazolyl] ester | 4-methylbenzoic acid [5-amino-1-(4-fluorophenyl)sulfonyl-pyrazol-3-yl] ester | MLS000936137 | SMR000620881 | [5-amino-1-(4-fluorophenyl)sulfonylpyrazol-3-yl] 4-methylbenzoate | [5-azanyl-1-(4-fluorophenyl)sulfonyl-pyrazol-3-yl] 4-methylbenzoate | cid_4152828 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14FN3O4S |
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| Mol. Mass. | 375.374 |
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| SMILES | Cc1ccc(cc1)C(=O)Oc1cc(N)n(n1)S(=O)(=O)c1ccc(F)cc1 |
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| Structure | 
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