| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
|---|
| Ligand | BDBM83673 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
|---|
| EC50 | 9870±n/a nM |
|---|
| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Endoribonuclease toxin MazF |
|---|
| Name: | Endoribonuclease toxin MazF |
|---|
| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 12100.43 |
|---|
| Organism: | Escherichia coli str. K-12 substr. MG1655 |
|---|
| Description: | gi_16130689 |
|---|
| Residue: | 111 |
|---|
| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
|
|
|
|---|
| BDBM83673 |
|---|
| n/a |
|---|
| Name | BDBM83673 |
|---|
| Synonyms: | 3-(5-methylfuran-2-yl)carbonyl-2-(4-methylphenyl)-1-(5-methylsulfanyl-1,3,4-thiadiazol-2-yl)-4-oxidanyl-2H-pyrrol-5-one | 3-hydroxy-4-(5-methyl-2-furoyl)-1-[5-(methylthio)-1,3,4-thiadiazol-2-yl]-5-(p-tolyl)-3-pyrrolin-2-one | 4-hydroxy-3-(5-methylfuran-2-carbonyl)-2-(4-methylphenyl)-1-(5-methylsulfanyl-1,3,4-thiadiazol-2-yl)-2H-pyrrol-5-one | 4-hydroxy-3-[(5-methyl-2-furanyl)-oxomethyl]-2-(4-methylphenyl)-1-[5-(methylthio)-1,3,4-thiadiazol-2-yl]-2H-pyrrol-5-one | MLS001140748 | SMR000650392 | cid_4902571 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H17N3O4S2 |
|---|
| Mol. Mass. | 427.497 |
|---|
| SMILES | CSc1nnc(s1)N1C(C(C(=O)c2ccc(C)o2)C(=O)C1=O)c1ccc(C)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
