Reaction Details |
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Target | Endoribonuclease toxin MazF |
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Ligand | BDBM83692 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
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EC50 | 3830±n/a nM |
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Citation | PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Endoribonuclease toxin MazF |
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Name: | Endoribonuclease toxin MazF |
Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 12100.43 |
Organism: | Escherichia coli str. K-12 substr. MG1655 |
Description: | gi_16130689 |
Residue: | 111 |
Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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BDBM83692 |
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n/a |
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Name | BDBM83692 |
Synonyms: | MLS002425460 | SMR001371386 | cid_44142831 |
Type | Small organic molecule |
Emp. Form. | C29H27FN2O3 |
Mol. Mass. | 470.5347 |
SMILES | [H][C@]12COc3ccc(C)cc3[C@]1([H])N1C(=O)CN(Cc3ccc(F)cc3)C(=O)[C@@]1(C)[C@H]2c1ccccc1 |
Structure |
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