Reaction Details |
| Report a problem with these data |
Target | Endoribonuclease toxin MazF |
---|
Ligand | BDBM83711 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
---|
EC50 | 4720±n/a nM |
---|
Citation | PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Endoribonuclease toxin MazF |
---|
Name: | Endoribonuclease toxin MazF |
Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 12100.43 |
Organism: | Escherichia coli str. K-12 substr. MG1655 |
Description: | gi_16130689 |
Residue: | 111 |
Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
|
|
|
BDBM83711 |
---|
n/a |
---|
Name | BDBM83711 |
Synonyms: | MLS002425477 | SMR001371403 | cid_45479837 |
Type | Small organic molecule |
Emp. Form. | C26H27BrN2O5 |
Mol. Mass. | 527.407 |
SMILES | [H][C@]12COc3ccc(Br)cc3[C@@]1([H])N1C(=O)CN(Cc3ccc(C)cc3)C(=O)[C@@]1(C)[C@H]2C(=O)OCC |
Structure |
|