Reaction Details |
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Target | Endoribonuclease toxin MazF |
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Ligand | BDBM83596 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen |
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EC50 | 9490±n/a nM |
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Citation | PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Endoribonuclease toxin MazF |
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Name: | Endoribonuclease toxin MazF |
Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 12100.43 |
Organism: | Escherichia coli str. K-12 substr. MG1655 |
Description: | gi_16130689 |
Residue: | 111 |
Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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BDBM83596 |
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n/a |
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Name | BDBM83596 |
Synonyms: | (5Z)-1-cyclohexyl-5-[(E)-3-phenylazanylprop-2-enylidene]-1,3-diazinane-2,4,6-trione | (5Z)-5-[(E)-3-anilinoprop-2-enylidene]-1-cyclohexyl-1,3-diazinane-2,4,6-trione | (5Z)-5-[(E)-3-anilinoprop-2-enylidene]-1-cyclohexyl-barbituric acid | 1-Cyclohexyl-5-[(E)-3-phenylamino-prop-2-en-(Z)-ylidene]-pyrimidine-2,4,6-trione | MLS000589654 | SMR000219487 | cid_5554345 |
Type | Small organic molecule |
Emp. Form. | C19H21N3O3 |
Mol. Mass. | 339.3883 |
SMILES | O=C1NC(=O)C(=CCC=Nc2ccccc2)C(=O)N1C1CCCCC1 |w:9.9,6.6| |
Structure |
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