Reaction Details |
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Target | Endoribonuclease toxin MazF |
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Ligand | BDBM83617 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen |
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EC50 | 10600±n/a nM |
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Citation | PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Endoribonuclease toxin MazF |
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Name: | Endoribonuclease toxin MazF |
Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 12100.43 |
Organism: | Escherichia coli str. K-12 substr. MG1655 |
Description: | gi_16130689 |
Residue: | 111 |
Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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BDBM83617 |
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n/a |
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Name | BDBM83617 |
Synonyms: | 2,4-dimethyl-3-(2-oxidanylidenepyrrolidin-1-yl)benzenesulfonohydrazide | 2,4-dimethyl-3-(2-oxo-1-pyrrolidinyl)benzenesulfonohydrazide | 2,4-dimethyl-3-(2-oxopyrrolidin-1-yl)benzenesulfonohydrazide | 3-(2-ketopyrrolidino)-2,4-dimethyl-benzenesulfonohydrazide | MLS000777818 | SMR000414206 | cid_3315168 |
Type | Small organic molecule |
Emp. Form. | C12H17N3O3S |
Mol. Mass. | 283.347 |
SMILES | Cc1ccc(c(C)c1N1CCCC1=O)S(=O)(=O)NN |
Structure |
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