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TargetEndoribonuclease toxin MazF
LigandBDBM53082
Substrate/Competitorn/a
Meas. Tech.Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen
EC50 8150±n/a nM
Citation PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,  Assay Method
 
Endoribonuclease toxin MazF
Name:Endoribonuclease toxin MazF
Synonyms:MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF
Type:Enzyme Catalytic Domain
Mol. Mass.:12100.43
Organism:Escherichia coli str. K-12 substr. MG1655
Description:gi_16130689
Residue:111
Sequence:
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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  Blast E-value cutoff:
BDBM53082
n/a
NameBDBM53082
Synonyms:4-Chloro-7-methyl-3-(phenyl-hydrazono)-1,3-dihydro-indol-2-one | 4-chloranyl-7-methyl-3-(2-phenylhydrazinyl)indol-2-one | 4-chloro-7-methyl-3-(2-phenylhydrazinyl)indol-2-one | 4-chloro-7-methyl-3-(N'-phenylhydrazino)indol-2-one | 4-chloro-7-methyl-3-(phenylhydrazo)-2-indolone | MLS001209448 | SMR000513316 | cid_5752240
TypeSmall organic molecule
Emp. Form.C15H12ClN3O
Mol. Mass.285.728
SMILESCc1ccc(Cl)c2=C(NNc3ccccc3)C(=O)N=c12 |c:6,t:19|
Structure
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