Reaction Details |
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Target | Endoribonuclease toxin MazF |
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Ligand | BDBM53082 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen |
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EC50 | 8150±n/a nM |
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Citation | PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Endoribonuclease toxin MazF |
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Name: | Endoribonuclease toxin MazF |
Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 12100.43 |
Organism: | Escherichia coli str. K-12 substr. MG1655 |
Description: | gi_16130689 |
Residue: | 111 |
Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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BDBM53082 |
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n/a |
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Name | BDBM53082 |
Synonyms: | 4-Chloro-7-methyl-3-(phenyl-hydrazono)-1,3-dihydro-indol-2-one | 4-chloranyl-7-methyl-3-(2-phenylhydrazinyl)indol-2-one | 4-chloro-7-methyl-3-(2-phenylhydrazinyl)indol-2-one | 4-chloro-7-methyl-3-(N'-phenylhydrazino)indol-2-one | 4-chloro-7-methyl-3-(phenylhydrazo)-2-indolone | MLS001209448 | SMR000513316 | cid_5752240 |
Type | Small organic molecule |
Emp. Form. | C15H12ClN3O |
Mol. Mass. | 285.728 |
SMILES | Cc1ccc(Cl)c2=C(NNc3ccccc3)C(=O)N=c12 |c:6,t:19| |
Structure |
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