| Reaction Details |
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 | Report a problem with these data |
| Target | Orotidine 5'-phosphate decarboxylase |
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| Ligand | BDBM83828 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter |
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| EC50 | >59638±n/a nM |
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| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Orotidine 5'-phosphate decarboxylase |
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| Name: | Orotidine 5'-phosphate decarboxylase |
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| Synonyms: | FXN frataxin | PYRF_ASPNG | pyrA | pyrG |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 30195.13 |
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| Organism: | Aspergillus niger |
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| Description: | gi_2395 |
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| Residue: | 277 |
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| Sequence: | MSSKSQLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAV
IKTHIDILSDFSDETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHRGTLRISEWAHI
INCSILPGEGIVEALAQTASAPDFSYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKY
KNFVMGFVSTRSLGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPASAIGRGA
DFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGN
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| BDBM83828 |
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| n/a |
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| Name | BDBM83828 |
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| Synonyms: | MLS002245437 | N-[3-(diethylsulfamoyl)-4-methyl-phenyl]-2-[(3,5-dimethyl-1,2-oxazol-4-yl)methylsulfanyl]ethanamide | N-[3-(diethylsulfamoyl)-4-methyl-phenyl]-2-[(3,5-dimethylisoxazol-4-yl)methylthio]acetamide | N-[3-(diethylsulfamoyl)-4-methylphenyl]-2-[(3,5-dimethyl-1,2-oxazol-4-yl)methylsulfanyl]acetamide | N-[3-(diethylsulfamoyl)-4-methylphenyl]-2-[(3,5-dimethyl-4-isoxazolyl)methylthio]acetamide | SMR001309089 | cid_4963639 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H27N3O4S2 |
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| Mol. Mass. | 425.565 |
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| SMILES | CCN(CC)S(=O)(=O)c1cc(NC(=O)CSCc2c(C)noc2C)ccc1C |
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| Structure | 
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