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TargetOrotidine 5'-phosphate decarboxylase
LigandBDBM77170
Substrate/Competitorn/a
Meas. Tech.Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter
EC50>59616±n/a nM
Citation PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,  Assay Method
 
Orotidine 5'-phosphate decarboxylase
Name:Orotidine 5'-phosphate decarboxylase
Synonyms:FXN frataxin | PYRF_ASPNG | pyrA | pyrG
Type:Enzyme Catalytic Domain
Mol. Mass.:30195.13
Organism:Aspergillus niger
Description:gi_2395
Residue:277
Sequence:
MSSKSQLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAV
IKTHIDILSDFSDETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHRGTLRISEWAHI
INCSILPGEGIVEALAQTASAPDFSYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKY
KNFVMGFVSTRSLGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPASAIGRGA
DFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGN
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  Blast E-value cutoff:
BDBM77170
n/a
NameBDBM77170
Synonyms:MLS000529376 | N-(2-furanylmethyl)-1-[1-(2-methylbutan-2-yl)-5-tetrazolyl]-1-(4-methylphenyl)-N-(thiophen-2-ylmethyl)methanamine | N-(furan-2-ylmethyl)-1-[1-(2-methylbutan-2-yl)-1,2,3,4-tetrazol-5-yl]-1-(4-methylphenyl)-N-(thiophen-2-ylmethyl)methanamine | N-(furan-2-ylmethyl)-1-[1-(2-methylbutan-2-yl)tetrazol-5-yl]-1-(4-methylphenyl)-N-(thiophen-2-ylmethyl)methanamine | SMR000121851 | [(1-tert-amyltetrazol-5-yl)-(p-tolyl)methyl]-(2-furfuryl)-(2-thenyl)amine | cid_3193727 | {[1-(1,1-Dimethyl-propyl)-1H-tetrazol-5-yl]-p-tolyl-methyl}-furan-2-ylmethyl-thiophen-2-ylmethyl-amine
TypeSmall organic molecule
Emp. Form.C24H29N5OS
Mol. Mass.435.585
SMILESCCC(C)(C)n1nnnc1C(N(Cc1ccco1)Cc1cccs1)c1ccc(C)cc1
Structure
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