Reaction Details |
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Target | Orotidine 5'-phosphate decarboxylase |
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Ligand | BDBM77170 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter |
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EC50 | >59616±n/a nM |
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Citation | PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Orotidine 5'-phosphate decarboxylase |
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Name: | Orotidine 5'-phosphate decarboxylase |
Synonyms: | FXN frataxin | PYRF_ASPNG | pyrA | pyrG |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 30195.13 |
Organism: | Aspergillus niger |
Description: | gi_2395 |
Residue: | 277 |
Sequence: | MSSKSQLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAV
IKTHIDILSDFSDETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHRGTLRISEWAHI
INCSILPGEGIVEALAQTASAPDFSYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKY
KNFVMGFVSTRSLGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPASAIGRGA
DFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGN
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BDBM77170 |
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n/a |
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Name | BDBM77170 |
Synonyms: | MLS000529376 | N-(2-furanylmethyl)-1-[1-(2-methylbutan-2-yl)-5-tetrazolyl]-1-(4-methylphenyl)-N-(thiophen-2-ylmethyl)methanamine | N-(furan-2-ylmethyl)-1-[1-(2-methylbutan-2-yl)-1,2,3,4-tetrazol-5-yl]-1-(4-methylphenyl)-N-(thiophen-2-ylmethyl)methanamine | N-(furan-2-ylmethyl)-1-[1-(2-methylbutan-2-yl)tetrazol-5-yl]-1-(4-methylphenyl)-N-(thiophen-2-ylmethyl)methanamine | SMR000121851 | [(1-tert-amyltetrazol-5-yl)-(p-tolyl)methyl]-(2-furfuryl)-(2-thenyl)amine | cid_3193727 | {[1-(1,1-Dimethyl-propyl)-1H-tetrazol-5-yl]-p-tolyl-methyl}-furan-2-ylmethyl-thiophen-2-ylmethyl-amine |
Type | Small organic molecule |
Emp. Form. | C24H29N5OS |
Mol. Mass. | 435.585 |
SMILES | CCC(C)(C)n1nnnc1C(N(Cc1ccco1)Cc1cccs1)c1ccc(C)cc1 |
Structure |
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