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TargetOrotidine 5'-phosphate decarboxylase
LigandBDBM67846
Substrate/Competitorn/a
Meas. Tech.Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter
EC50>59633±n/a nM
Citation PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,  Assay Method
 
Orotidine 5'-phosphate decarboxylase
Name:Orotidine 5'-phosphate decarboxylase
Synonyms:FXN frataxin | PYRF_ASPNG | pyrA | pyrG
Type:Enzyme Catalytic Domain
Mol. Mass.:30195.13
Organism:Aspergillus niger
Description:gi_2395
Residue:277
Sequence:
MSSKSQLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAV
IKTHIDILSDFSDETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHRGTLRISEWAHI
INCSILPGEGIVEALAQTASAPDFSYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKY
KNFVMGFVSTRSLGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPASAIGRGA
DFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGN
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  Blast E-value cutoff:
BDBM67846
n/a
NameBDBM67846
Synonyms:2,7-Bis-(4-methyl-piperidine-1-sulfonyl)-fluoren-9-one oxime | 2,7-bis[(4-methyl-1-piperidinyl)sulfonyl]-9-fluorenone oxime | 2,7-bis[(4-methylpiperidino)sulfonyl]fluoren-9-one oxime | MLS000551434 | N-[2,7-bis[(4-methylpiperidin-1-yl)sulfonyl]fluoren-9-ylidene]hydroxylamine | SMR000145359 | cid_1540666
TypeSmall organic molecule
Emp. Form.C25H31N3O5S2
Mol. Mass.517.661
SMILESCC1CCN(CC1)S(=O)(=O)c1ccc-2c(c1)C(N=O)c1cc(ccc-21)S(=O)(=O)N1CCC(C)CC1
Structure
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