BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetOrotidine 5'-phosphate decarboxylase
LigandBDBM83841
Substrate/Competitorn/a
Meas. Tech.Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter
EC50>59674±n/a nM
Citation PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,  Assay Method
 
Orotidine 5'-phosphate decarboxylase
Name:Orotidine 5'-phosphate decarboxylase
Synonyms:FXN frataxin | PYRF_ASPNG | pyrA | pyrG
Type:Enzyme Catalytic Domain
Mol. Mass.:30195.13
Organism:Aspergillus niger
Description:gi_2395
Residue:277
Sequence:
MSSKSQLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAV
IKTHIDILSDFSDETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHRGTLRISEWAHI
INCSILPGEGIVEALAQTASAPDFSYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKY
KNFVMGFVSTRSLGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPASAIGRGA
DFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM83841
n/a
NameBDBM83841
Synonyms:MLS002701804 | SMR001565398 | cid_5477390
TypeSmall organic molecule
Emp. Form.C31H41ClN2O9
Mol. Mass.621.118
SMILES[H]C12CC(O)(NC(=O)O1)C(OC)\C=C\C=C(C)\Cc1cc(O)c(Cl)c(c1)N(C)C(=O)CC(OC(=O)C(C)C)C1(C)OC1C2C |c:15,t:13|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: