| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Orotidine 5'-phosphate decarboxylase |
|---|
| Ligand | BDBM50154618 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter |
|---|
| EC50 | >59587±n/a nM |
|---|
| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Orotidine 5'-phosphate decarboxylase |
|---|
| Name: | Orotidine 5'-phosphate decarboxylase |
|---|
| Synonyms: | FXN frataxin | PYRF_ASPNG | pyrA | pyrG |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 30195.13 |
|---|
| Organism: | Aspergillus niger |
|---|
| Description: | gi_2395 |
|---|
| Residue: | 277 |
|---|
| Sequence: | MSSKSQLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAV
IKTHIDILSDFSDETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHRGTLRISEWAHI
INCSILPGEGIVEALAQTASAPDFSYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKY
KNFVMGFVSTRSLGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPASAIGRGA
DFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGN
|
|
|
|---|
| BDBM50154618 |
|---|
| n/a |
|---|
| Name | BDBM50154618 |
|---|
| Synonyms: | 5-Bromo-3-(2-oxo-2-phenyl-ethylidene)-1,3-dihydro-indol-2-one | 5-bromo-3-(2-oxo-2-phenylethylidene)indolin-2-one | CHEMBL363491 | cid_5477132 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H10BrNO2 |
|---|
| Mol. Mass. | 328.16 |
|---|
| SMILES | Brc1ccc2NC(=O)\C(=C/C(=O)c3ccccc3)c2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
