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TargetOrotidine 5'-phosphate decarboxylase
LigandBDBM83848
Substrate/Competitorn/a
Meas. Tech.Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter
EC50>59516±n/a nM
Citation PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,  Assay Method
 
Orotidine 5'-phosphate decarboxylase
Name:Orotidine 5'-phosphate decarboxylase
Synonyms:FXN frataxin | PYRF_ASPNG | pyrA | pyrG
Type:Enzyme Catalytic Domain
Mol. Mass.:30195.13
Organism:Aspergillus niger
Description:gi_2395
Residue:277
Sequence:
MSSKSQLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAV
IKTHIDILSDFSDETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHRGTLRISEWAHI
INCSILPGEGIVEALAQTASAPDFSYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKY
KNFVMGFVSTRSLGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPASAIGRGA
DFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGN
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  Blast E-value cutoff:
BDBM83848
n/a
NameBDBM83848
Synonyms:MLS002702310 | N-[2-(dimethylamino)ethyl]-1-methoxy-4-acridinecarboxamide;hydrochloride | N-[2-(dimethylamino)ethyl]-1-methoxy-acridine-4-carboxamide;hydrochloride | N-[2-(dimethylamino)ethyl]-1-methoxyacridine-4-carboxamide;hydrochloride | SMR001565872 | cid_386514
TypeSmall organic molecule
Emp. Form.C19H21N3O2
Mol. Mass.323.3889
SMILESCOc1ccc(C(=O)NCCN(C)C)c2nc3ccccc3cc12
Structure
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