| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Orotidine 5'-phosphate decarboxylase |
|---|
| Ligand | BDBM50151720 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter |
|---|
| EC50 | >59600±n/a nM |
|---|
| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Orotidine 5'-phosphate decarboxylase |
|---|
| Name: | Orotidine 5'-phosphate decarboxylase |
|---|
| Synonyms: | FXN frataxin | PYRF_ASPNG | pyrA | pyrG |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 30195.13 |
|---|
| Organism: | Aspergillus niger |
|---|
| Description: | gi_2395 |
|---|
| Residue: | 277 |
|---|
| Sequence: | MSSKSQLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAV
IKTHIDILSDFSDETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHRGTLRISEWAHI
INCSILPGEGIVEALAQTASAPDFSYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKY
KNFVMGFVSTRSLGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPASAIGRGA
DFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGN
|
|
|
|---|
| BDBM50151720 |
|---|
| n/a |
|---|
| Name | BDBM50151720 |
|---|
| Synonyms: | ARFORMOTEROL TARTRATE | CHEMBL1363 | CHEMBL605993 | FORMOTEROL | FORMOTEROL FUMARATE | Foradil | N-(2-Hydroxy-5-{1-hydroxy-2-[2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenyl)-formamide | N-(2-hydroxy-5-((R)-1-hydroxy-2-((R)-1-(4-methoxyphenyl)propan-2-ylamino)ethyl)phenyl)formamide | Symbicort | cid_9912089 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H24N2O4 |
|---|
| Mol. Mass. | 344.4049 |
|---|
| SMILES | COc1ccc(C[C@@H](C)NC[C@H](O)c2ccc(O)c(NC=O)c2)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
