| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protein kinase C delta type |
|---|
| Ligand | BDBM3149 |
|---|
| Substrate/Competitor | Lysine-rich histone |
|---|
| Meas. Tech. | PKC assay |
|---|
| IC50 | 32±n/a nM |
|---|
| Citation |  Lai, YS; Menaldino, DS; Nichols, JB; Jagdmann , GE; Mylott, F; Gillespie, J; Hall, SE Ring Size effect in the PKC inhibitory activities of perhydroazepine analogs of balanol. Bioorg Med Chem Lett5:2151-4 (1995) Article |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Protein kinase C delta type |
|---|
| Name: | Protein kinase C delta type |
|---|
| Synonyms: | KPCD_HUMAN | PKC delta | PKCD | PRKCD | Protein Kinase C- delta | Protein kinase C, PKC; classical/novel | nPKC-delta |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 77516.79 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | The recombinant human PKC enzymes were
produced using a baculovirus expression system in SF9 cells |
|---|
| Residue: | 676 |
|---|
| Sequence: | MAPFLRIAFNSYELGSLQAEDEANQPFCAVKMKEALSTERGKTLVQKKPTMYPEWKSTFD
AHIYEGRVIQIVLMRAAEEPVSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMSVQY
FLEDVDCKQSMRSEDEAKFPTMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKDFVW
GLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTAANSRDTIFQKERFNIDMPHRFKVHNYMS
PTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCGINQKLLAEALNQVTQRASR
RSDSASSEPVGIYQGFEKKTGVAGEDMQDNSGTYGKIWEGSSKCNINNFIFHKVLGKGSF
GKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVLTLAAENPFLTHLICTFQTK
DHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGIIYRDLKLDNVL
LDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYE
MLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFEREPTKRLGVTGNIKIH
PFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQEFLNEKARLSYSDKNLIDSMDQSAF
AGFSFVNPKFEHLLED
|
|
|
|---|
| BDBM3149 |
|---|
| Lysine-rich histone |
|---|
| Name: | Lysine-rich histone |
|---|
| Synonyms: | ING Peptide | Lys-rich histone | histone type IIIS |
|---|
| Type: | Peptide |
|---|
| Mol. Mass.: | 10508.21 |
|---|
| Organism: | Bos taurus (bovine) |
|---|
| Description: | Purified as a lysine rich fraction of histone H1 from calf thymus.
|
|---|
| Residue: | 105 |
|---|
| Sequence: | SETAPAAPAAAPPAEKTPVKKKAAKKPAGARRKASGPPVSELITKAVAASKERSGVSLAA
LKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFK
|
|
|
|---|
Search and Browse
