| Reaction Details |
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 | Report a problem with these data |
| Target | Protein kinase C eta type |
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| Ligand | BDBM3150 |
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| Substrate/Competitor | Lysine-rich histone |
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| Meas. Tech. | PKC assay |
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| IC50 | 60±n/a nM |
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| Citation |  Lai, YS; Menaldino, DS; Nichols, JB; Jagdmann , GE; Mylott, F; Gillespie, J; Hall, SE Ring Size effect in the PKC inhibitory activities of perhydroazepine analogs of balanol. Bioorg Med Chem Lett5:2151-4 (1995) Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Protein kinase C eta type |
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| Name: | Protein kinase C eta type |
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| Synonyms: | KPCL_HUMAN | PKC-L | PKCL | PRKCH | PRKCL | Protein Kinase C, eta | Protein kinase C, PKC; classical/novel | nPKC-eta |
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| Type: | Enzyme |
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| Mol. Mass.: | 77844.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | The recombinant human PKC enzymes were
produced using a baculovirus expression system in SF9 cells |
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| Residue: | 683 |
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| Sequence: | MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRHSLFKKGHQLLDPYLTVSVDQVRVGQTSTK
QKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCTLQFQELLRTTGASDTFEG
WVDLEPEGKVFVVITLTGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQINGHKFMATYLR
QPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDSKIAEQRF
GINIPHKFSIHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAV
ELAKTLAGMGLQPGNISPTSKLVSRSTLRRQGKESSKEGNGIGVNSSNRLGIDNFEFIRV
LGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLF
CCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDL
KLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAM
GVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSL
TQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNFDPDFIKEEPVLTPIDE
GHLPMINQDEFRNFSYVSPELQP
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| BDBM3150 |
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| Lysine-rich histone |
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| Name: | Lysine-rich histone |
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| Synonyms: | ING Peptide | Lys-rich histone | histone type IIIS |
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| Type: | Peptide |
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| Mol. Mass.: | 10508.21 |
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| Organism: | Bos taurus (bovine) |
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| Description: | Purified as a lysine rich fraction of histone H1 from calf thymus.
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| Residue: | 105 |
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| Sequence: | SETAPAAPAAAPPAEKTPVKKKAAKKPAGARRKASGPPVSELITKAVAASKERSGVSLAA
LKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFK
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