| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM83682 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis of small molecule activators of the MazEF TA System via a fluorescence-based single-stranded RNase assay |
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| EC50 | 5150±n/a nM |
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| Citation |  PubChem, PC SAR analysis of small molecule activators of the MazEF TA System via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM83682 |
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| n/a |
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| Name | BDBM83682 |
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| Synonyms: | 2-(3-Cyano-quinolin-2-ylsulfanyl)-N-(2-morpholin-4-yl-phenyl)-acetamide | 2-(3-cyanoquinolin-2-yl)sulfanyl-N-(2-morpholin-4-ylphenyl)acetamide | 2-(3-cyanoquinolin-2-yl)sulfanyl-N-(2-morpholin-4-ylphenyl)ethanamide | 2-[(3-cyano-2-quinolinyl)thio]-N-[2-(4-morpholinyl)phenyl]acetamide | 2-[(3-cyano-2-quinolyl)thio]-N-(2-morpholinophenyl)acetamide | MLS001385496 | SMR000007880 | cid_648877 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20N4O2S |
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| Mol. Mass. | 404.485 |
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| SMILES | O=C(CSc1nc2ccccc2cc1C#N)Nc1ccccc1N1CCOCC1 |
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| Structure | 
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