| Reaction Details |
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 | Report a problem with these data |
| Target | Multidrug efflux pump |
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| Ligand | BDBM78662 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Mdr1 with Hit compounds from Cherry Pick1 |
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| EC50 | 14±n/a nM |
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| Citation |  PubChem, PC Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Mdr1 with Hit compounds from Cherry Pick1 PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Multidrug efflux pump |
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| Name: | Multidrug efflux pump |
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| Synonyms: | Candida albicans strain ATCC 10261 multidrug efflux pump (MDR1) gene, MDR1-A allele, complete cds |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 62915.82 |
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| Organism: | Candida albicans |
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| Description: | Q09GR2 |
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| Residue: | 564 |
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| Sequence: | MHYRFLRDSFVGRVTYHLSKHKYFAHPEEAKDYIVPEKYLADYKPTLADDTSINFEKEEI
DNQGEPNSSQSSSSNNTIVDNNNNNDNDVDGDKIVVTWDGDDDPENPQNWPTLQKAFFIF
QISFLTTSVYMGSAVYTPGIEELMHDFGIGRVVATLPLTLFVIGYGVGPLVFSPMSENAI
FGRTSIYIITLFLFVILQIPTALVNNIAGLCILRFLGGFFASPCLATGGASVADVVKFWN
LPVGLAAWSLGAVCGPSFGPFFGSILTVKASWRWTFWFMCIISGFSFVMLCFTLPETFGK
TLLYRKAKRLRAITGNDRITSEGEIENSKMTSHELIIDTLWRPLEITVMEPVVLLINIYI
AMVYSILYLFFEVFPIYFVGVKHFTLVELGTTYMSIVIGIVIAAFIYIPVIRQKFTKPIL
RQEQVFPEVFIPIAIVGGILLTSGLFIFGWSANRTTHWVGPLFGAATTASGAFLIFQTLF
NFMGASFKPHYIASVFASNDLFRSVIASVFPLFGAPLFDNLATPEYPVAWGSSVLGFITL
VMIAIPVLFYLNGPKLRARSKYAN
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|
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| BDBM78662 |
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| n/a |
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| Name | BDBM78662 |
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| Synonyms: | 2-[3-(3,4-dichlorophenyl)-6,7-dihydro-5H-pyrrol[1,2-a]imidazol-1-ium-1-yl]-1-phenothiazin-10-yl-ethanone;chloride | 2-[3-(3,4-dichlorophenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-1-ium-1-yl]-1-(10-phenothiazinyl)ethanone;chloride | 2-[3-(3,4-dichlorophenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-1-ium-1-yl]-1-phenothiazin-10-yl-ethanone;chloride | 2-[3-(3,4-dichlorophenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-1-ium-1-yl]-1-phenothiazin-10-ylethanone;chloride | 3-(3,4-Dichloro-phenyl)-1-(2-oxo-2-phenothiazin-10-yl-ethyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-1-ium | MLS000580307 | SMR000220459 | cid_12005680 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H20Cl2N3OS |
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| Mol. Mass. | 493.427 |
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| SMILES | Clc1ccc(cc1Cl)-c1c[n+](CC(=O)N2c3ccccc3Sc3ccccc23)c2CCCn12 |
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| Structure | 
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