| Reaction Details |
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 | Report a problem with these data |
| Target | Multidrug efflux pump |
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| Ligand | BDBM84147 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Mdr1 with Hit compounds from Cherry Pick1 |
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| EC50 | 3990±n/a nM |
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| Citation |  PubChem, PC Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Mdr1 with Hit compounds from Cherry Pick1 PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Multidrug efflux pump |
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| Name: | Multidrug efflux pump |
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| Synonyms: | Candida albicans strain ATCC 10261 multidrug efflux pump (MDR1) gene, MDR1-A allele, complete cds |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 62915.82 |
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| Organism: | Candida albicans |
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| Description: | Q09GR2 |
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| Residue: | 564 |
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| Sequence: | MHYRFLRDSFVGRVTYHLSKHKYFAHPEEAKDYIVPEKYLADYKPTLADDTSINFEKEEI
DNQGEPNSSQSSSSNNTIVDNNNNNDNDVDGDKIVVTWDGDDDPENPQNWPTLQKAFFIF
QISFLTTSVYMGSAVYTPGIEELMHDFGIGRVVATLPLTLFVIGYGVGPLVFSPMSENAI
FGRTSIYIITLFLFVILQIPTALVNNIAGLCILRFLGGFFASPCLATGGASVADVVKFWN
LPVGLAAWSLGAVCGPSFGPFFGSILTVKASWRWTFWFMCIISGFSFVMLCFTLPETFGK
TLLYRKAKRLRAITGNDRITSEGEIENSKMTSHELIIDTLWRPLEITVMEPVVLLINIYI
AMVYSILYLFFEVFPIYFVGVKHFTLVELGTTYMSIVIGIVIAAFIYIPVIRQKFTKPIL
RQEQVFPEVFIPIAIVGGILLTSGLFIFGWSANRTTHWVGPLFGAATTASGAFLIFQTLF
NFMGASFKPHYIASVFASNDLFRSVIASVFPLFGAPLFDNLATPEYPVAWGSSVLGFITL
VMIAIPVLFYLNGPKLRARSKYAN
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| BDBM84147 |
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| n/a |
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| Name | BDBM84147 |
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| Synonyms: | 2,6-Dichloro-4-(1,2-dihydro-3,9,9a-triaza-fluoren-4-yl)-phenylamine | 2,6-bis(chloranyl)-4-(3,4-dihydropyrazino[1,2-b]indazol-1-yl)aniline | 2,6-dichloro-4-(3,4-dihydropyrazino[1,2-b]indazol-1-yl)aniline | MLS001101506 | SMR001216730 | [2,6-dichloro-4-(3,4-dihydropyrazin[1,2-b]indazol-1-yl)phenyl]amine | cid_24979614 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12Cl2N4 |
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| Mol. Mass. | 331.199 |
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| SMILES | Nc1c(Cl)cc(cc1Cl)C1=NCCn2nc3ccccc3c12 |t:10| |
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| Structure | 
|
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