| Reaction Details |
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 | Report a problem with these data |
| Target | Kit ligand |
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| Ligand | BDBM84553 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| pH | 7±0 |
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| Temperature | 295.15±0 K |
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| IC50 | >1.0e+4±n/a nM |
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| Citation |  Jautelat, R; Brumby, T; Schäfer, M; Briem, H; Eisenbrand, G; Schwahn, S; Krüger, M; Lücking, U; Prien, O; Siemeister, G From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors. Chembiochem6:531-40 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Kit ligand |
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| Name: | Kit ligand |
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| Synonyms: | KITLG | MGF | Mast cell growth factor | SCF | SCF_HUMAN | c-Kit | c-Kit ligand |
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| Type: | Protein |
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| Mol. Mass.: | 30897.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21583 |
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| Residue: | 273 |
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| Sequence: | MKKTQTWILTCIYLQLLLFNPLVKTEGICRNRVTNNVKDVTKLVANLPKDYMITLKYVPG
MDVLPSHCWISEMVVQLSDSLTDLLDKFSNISEGLSNYSIIDKLVNIVDDLVECVKENSS
KDLKKSFKSPEPRLFTPEEFFRIFNRSIDAFKDFVVASETSDCVVSSTLSPEKDSRVSVT
KPFMLPPVAASSLRNDSSSSNRKAKNPPGDSSLHWAAMALPALFSLIIGFAFGALYWKKR
QPSLTRAVENIQINEEDNEISMLQEKEREFQEV
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| BDBM84553 |
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| n/a |
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| Name | BDBM84553 |
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| Synonyms: | Indirubin derivative, 28a | Indirubin derivative, 28b |
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| Type | Small organic molecule |
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| Emp. Form. | C22H26N4O4S |
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| Mol. Mass. | 442.531 |
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| SMILES | CN(C)CCN(C)S(=O)(=O)c1ccc2NC(=O)C(C3=Nc4ccccc4C3(C)O)c2c1 |t:18| |
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| Structure | 
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