| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1E |
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| Ligand | BDBM78940 |
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| Substrate/Competitor | n/a |
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| Ki | 200±n/a nM |
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| Comments | PDSP_1219 |
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| Citation |  Lovenberg, TW; Erlander, MG; Baron, BM; Racke, M; Slone, AL; Siegel, BW; Craft, CM; Burns, JE; Danielson, PE; Sutcliffe, JG Molecular cloning and functional expression of 5-HT1E-like rat and human 5-hydroxytryptamine receptor genes. Proc Natl Acad Sci U S A90:2184-8 (1993) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 1E |
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| Name: | 5-hydroxytryptamine receptor 1E |
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| Synonyms: | 5-HT1E | HTR1E |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41709.22 |
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| Organism: | RAT |
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| Description: | 5-HT1E HTR1E RAT::G5B6Z9 |
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| Residue: | 365 |
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| Sequence: | MNLTNYTTEASVAVKPKTVTEKMLICMTLVIITTLTMLLNSAVIMAICTTRKLHQPANYL
ICSLAVTDLLVAVLVMPLSVMYIVMDNWRLGYFICEVWLSVDMTCCTCSILHLCVIALDR
YWAITKAIEYARKRTARRAGLMILTVWTISIFISMPPLFWRSHRQVSPPPSQCTIQHDHV
IYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQ
TFCVSDFSTSDPTTEFEKIHTSIRIPPFDNDLDQPGERQQISSTRERKAARILGLILGAF
ILSWLPFFIKELIVGLSIYTVSSEVGDFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIR
CREHT
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| BDBM78940 |
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| n/a |
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| Name | BDBM78940 |
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| Synonyms: | METHIOTHEPIN | MLS000859918 | Methiothepin mesylate salt | SMR000326779 | cid_3039995 | mesylic acid;1-methyl-4-[3-(methylthio)-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine | methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine | methanesulfonic acid;1-methyl-4-[3-(methylthio)-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24N2S2 |
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| Mol. Mass. | 356.548 |
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| SMILES | CSc1ccc2Sc3ccccc3CC(N3CCN(C)CC3)c2c1 |
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| Structure | 
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