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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50000068
Substrate/Competitorn/a
Meas. Tech.ChEBML_226551
Ki 0.260000±n/a nM
Citation de Costa BRRadesca LDi Paolo LBowen WD Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1-pyrrolidinyl)ethylamines: structural requirements and binding affinity at the sigma receptor. J Med Chem 35:38-47 (1992) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma non-opioid intracellular receptor 1
Synonyms:Aging-associated gene 8 protein | SIG-1R | SR-BP | SR31747-binding protein | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:Enzyme Catalytic Domain
Mol. Mass.:25124.85
Organism:Homo sapiens (Human)
Description:Sigma 0 HUMAN::Q99720
Residue:223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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  Blast E-value cutoff:
BDBM50000068
n/a
NameBDBM50000068
Synonyms:CHEMBL142700 | [2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-piperidin-1-yl-ethyl)-amine
TypeSmall organic molecule
Emp. Form.C16H24Cl2N2
Mol. Mass.315.281
SMILESCN(CCN1CCCCC1)CCc1ccc(Cl)c(Cl)c1
Structure
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