| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM50239274 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1665869 (CHEMBL4015665) |
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| Ki | 0.490000±n/a nM |
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| Citation |  Bruno, E; Buemi, MR; Di Fiore, A; De Luca, L; Ferro, S; Angeli, A; Cirilli, R; Sadutto, D; Alterio, V; Monti, SM; Supuran, CT; De Simone, G; Gitto, R Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides. J Med Chem60:4316-4326 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM50239274 |
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| n/a |
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| Name | BDBM50239274 |
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| Synonyms: | CHEMBL4079453 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20N2O4S |
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| Mol. Mass. | 408.47 |
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| SMILES | NS(=O)(=O)c1ccc(cc1)C(=O)N1CCc2cc(O)ccc2C1c1ccccc1 |
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| Structure | 
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