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TargetCarbonic anhydrase
LigandBDBM50239275
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1665869
Ki 0.510000±n/a nM
Citation Bruno EBuemi MRDi Fiore ADe Luca LFerro SAngeli ACirilli RSadutto DAlterio VMonti SMSupuran CTDe Simone GGitto R Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides. J Med Chem 60:4316-4326 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase
Name:Carbonic anhydrase
Synonyms:CA-VII | CA7 | Carbonate dehydratase VII | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:Enzyme
Mol. Mass.:29664.11
Organism:Homo sapiens (Human)
Description:Human cloned isozyme.
Residue:264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50239275
n/a
NameBDBM50239275
Synonyms:CHEMBL4073364
TypeSmall organic molecule
Emp. Form.C22H19FN2O5S
Mol. Mass.442.46
SMILESNS(=O)(=O)c1ccc(cc1)C(=O)N1CCc2cc(O)c(O)cc2C1c1ccc(F)cc1
Structure
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