| Reaction Details |
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 | Report a problem with these data |
| Target | Lymphocyte antigen 96 |
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| Ligand | BDBM50239337 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1665929 (CHEMBL4015725) |
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| IC50 | 200±n/a nM |
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| Citation |  Sestito, SE; Facchini, FA; Morbioli, I; Billod, JM; Martin-Santamaria, S; Casnati, A; Sansone, F; Peri, F Amphiphilic Guanidinocalixarenes Inhibit Lipopolysaccharide (LPS)- and Lectin-Stimulated Toll-like Receptor 4 (TLR4) Signaling. J Med Chem60:4882-4892 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lymphocyte antigen 96 |
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| Name: | Lymphocyte antigen 96 |
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| Synonyms: | ESOP-1 | ESOP1 | ESOP1 | LY96 | LY96_HUMAN | Ly-96 | Lymphocyte antigen 96 | MD2 | Protein MD-2 | TLR4-MD2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 18551.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_107939 |
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| Residue: | 160 |
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| Sequence: | MLPFLFFSTLFSSIFTEAQKQYWVCNSSDASISYTYCDKMQYPISINVNPCIELKRSKGL
LHIFYIPRRDLKQLYFNLYITVNTMNLPKRKEVICRGSDDDYSFCRALKGETVNTTISFS
FKGIKFSKGKYKCVVEAISGSPEEMLFCLEFVILHQPNSN
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| BDBM50239337 |
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| n/a |
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| Name | BDBM50239337 |
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| Synonyms: | CHEMBL4072822 |
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| Type | Small organic molecule |
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| Emp. Form. | C64H104Cl4N12O4 |
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| Mol. Mass. | 1247.401 |
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| SMILES | Cl.Cl.Cl.Cl.CC(C)(C)c1cc2Cc3cc(cc(Cc4cc(cc(Cc5cc(cc(Cc(c1)c2OCCCCNC(N)=N)c5OCCCCNC(N)=N)C(C)(C)C)c4OCCCCNC(N)=N)C(C)(C)C)c3OCCCCNC(N)=N)C(C)(C)C |
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| Structure | 
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