Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetLymphocyte antigen 96
LigandBDBM50239341
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1665929
IC50 5700±n/a nM
Citation Sestito SEFacchini FAMorbioli IBillod JMMartin-Santamaria SCasnati ASansone FPeri F Amphiphilic Guanidinocalixarenes Inhibit Lipopolysaccharide (LPS)- and Lectin-Stimulated Toll-like Receptor 4 (TLR4) Signaling. J Med Chem 60:4882-4892 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Lymphocyte antigen 96
Name:Lymphocyte antigen 96
Synonyms:ESOP-1 | ESOP1 | LY96 | Ly-96 | Lymphocyte antigen 96 | MD2 | Protein MD-2
Type:PROTEIN
Mol. Mass.:18551.39
Organism:Homo sapiens (Human)
Description:ChEMBL_107939
Residue:160
Sequence:
MLPFLFFSTLFSSIFTEAQKQYWVCNSSDASISYTYCDKMQYPISINVNPCIELKRSKGL
LHIFYIPRRDLKQLYFNLYITVNTMNLPKRKEVICRGSDDDYSFCRALKGETVNTTISFS
FKGIKFSKGKYKCVVEAISGSPEEMLFCLEFVILHQPNSN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50239341
n/a
NameBDBM50239341
Synonyms:CHEMBL4105554
TypeSmall organic molecule
Emp. Form.C50H76Cl4N12O3
Mol. Mass.1035.029
SMILESCl.Cl.Cl.Cl.CCCCCCOc1c2Cc3cc(Cc4cc(NC(N)=N)cc(Cc5cc(NC(N)=N)cc(Cc1cc(NC(N)=N)c2)c5OCCCCCC)c4OCCCCCC)cc(NC(N)=N)c3
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: