| Reaction Details |
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 | Report a problem with these data |
| Target | Prolyl 4-hydroxylase subunit alpha-1 |
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| Ligand | BDBM26114 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_157457 (CHEMBL765597) |
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| IC50 | 5180±n/a nM |
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| Citation |  Cunliffe, CJ; Franklin, TJ; Hales, NJ; Hill, GB Novel inhibitors of prolyl 4-hydroxylase. 3. Inhibition by the substrate analogue N-oxaloglycine and its derivatives. J Med Chem35:2652-8 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Prolyl 4-hydroxylase subunit alpha-1 |
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| Name: | Prolyl 4-hydroxylase subunit alpha-1 |
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| Synonyms: | P4HA1_RAT | P4ha | P4ha1 | Prolyl 4-hydroxylase alpha-1 subunit |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60891.28 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_157460 |
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| Residue: | 534 |
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| Sequence: | MIWGVLMMGILLPQCSAHPGFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWA
EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGFISNLTIQRQY
FPNDEDQVGAAKALFRLQDTYNLDTNTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY
YHTELWMEQALMQLEEGEMSTVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR
ANGNLVYFEYIMSKEKDANKSASGDQSDQKTTPKKKGIAVDYLPERQKYEMLCRGEGIKM
TPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRL
SRATVHDPETGKLTTAQYRVSKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANY
GVGGQYEPHFDFARKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKG
TAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE
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| BDBM26114 |
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| n/a |
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| Name | BDBM26114 |
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| Synonyms: | CHEMBL88972 | pyridine carboxylate, 6b | pyridine-2,5-dicarboxylic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C7H5NO4 |
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| Mol. Mass. | 167.1189 |
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| SMILES | OC(=O)c1ccc(nc1)C(O)=O |
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| Structure | 
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