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TargetProlyl 4-hydroxylase alpha-1 subunit
LigandBDBM26114
Substrate/Competitorn/a
Meas. Tech.ChEBML_157461
Ki 800±n/a nM
Citation Cunliffe CJFranklin TJHales NJHill GB Novel inhibitors of prolyl 4-hydroxylase. 3. Inhibition by the substrate analogue N-oxaloglycine and its derivatives. J Med Chem 35:2652-8 (1992) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Prolyl 4-hydroxylase alpha-1 subunit
Name:Prolyl 4-hydroxylase alpha-1 subunit
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:60891.28
Organism:Rattus norvegicus
Description:ChEMBL_157460
Residue:534
Sequence:
MIWGVLMMGILLPQCSAHPGFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWA
EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGFISNLTIQRQY
FPNDEDQVGAAKALFRLQDTYNLDTNTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY
YHTELWMEQALMQLEEGEMSTVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR
ANGNLVYFEYIMSKEKDANKSASGDQSDQKTTPKKKGIAVDYLPERQKYEMLCRGEGIKM
TPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRL
SRATVHDPETGKLTTAQYRVSKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANY
GVGGQYEPHFDFARKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKG
TAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE
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  Blast E-value cutoff:
BDBM26114
n/a
NameBDBM26114
Synonyms:CHEMBL88972 | pyridine carboxylate, 6b | pyridine-2,5-dicarboxylic acid
TypeSmall organic molecule
Emp. Form.C7H5NO4
Mol. Mass.167.1189
SMILESOC(=O)c1ccc(nc1)C(O)=O
Structure
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