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TargetMuscarinic acetylcholine receptor M1
LigandBDBM50246672
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1676735 (CHEMBL4026878)
Ki 4500±n/a nM
Citation Fish, IStößel, AEitel, KValant, CAlbold, SHuebner, HMöller, DClark, MJSunahara, RKChristopoulos, AShoichet, BKGmeiner, P Structure-Based Design and Discovery of New M J Med Chem60:9239-9250 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Muscarinic acetylcholine receptor M1
Name:Muscarinic acetylcholine receptor M1
Synonyms:ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1
Type:Protein
Mol. Mass.:51442.54
Organism:Homo sapiens (Human)
Description:P11229
Residue:460
Sequence:
MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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  Blast E-value cutoff:
BDBM50246672
n/a
NameBDBM50246672
Synonyms:CHEMBL4094819
TypeSmall organic molecule
Emp. Form.C12H18ClNO2
Mol. Mass.243.73
SMILES[O-]C=O.C[N+](C)(C)CCc1cccc(Cl)c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: