| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 and M4 |
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| Ligand | BDBM10759 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1676736 |
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| Ki | 390±n/a nM |
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| Citation |  Fish I; Stößel A; Eitel K; Valant C; Albold S; Huebner H; Möller D; Clark MJ; Sunahara RK; Christopoulos A; Shoichet BK; Gmeiner P Structure-Based Design and Discovery of New M J Med Chem 60:9239-9250 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M2 and M4 |
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| Name: | Muscarinic acetylcholine receptor M2 and M5 |
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| Synonyms: | CHRM2 | Cholinergic, muscarinic M2 | RecName: Full=Muscarinic acetylcholine receptor M2 |
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| Type: | GPCR |
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| Mol. Mass.: | 51730.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08172 |
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| Residue: | 466 |
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| Sequence: | MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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| BDBM10759 |
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| n/a |
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| Name | BDBM10759 |
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| Synonyms: | 2-acetoxyethyl(trimethyl)ammonium;bromide | 2-acetoxyethyl(trimethyl)ammonium;perchlorate | CHEMBL667 | [2-(acetyloxy)ethyl]trimethylazanium | acetylcholine | acetylcholine chloride | cid_6060 |
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| Type | Small Organic Molecule |
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| Emp. Form. | C7H16NO2 |
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| Mol. Mass. | 146.2069 |
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| SMILES | CC(=O)OCC[N+](C)(C)C |
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| Structure | 
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