| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50242120 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1671313 (CHEMBL4021342) |
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| Ki | 1.6±n/a nM |
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| Citation |  Basu, S; Barawkar, DA; Ramdas, V; Patel, M; Waman, Y; Panmand, A; Kumar, S; Thorat, S; Naykodi, M; Goswami, A; Reddy, BS; Prasad, V; Chaturvedi, S; Quraishi, A; Menon, S; Paliwal, S; Kulkarni, A; Karande, V; Ghosh, I; Mustafa, S; De, S; Jain, V; Banerjee, ER; Rouduri, SR; Palle, VP; Chugh, A; Mookhtiar, KA Design and synthesis of novel xanthine derivatives as potent and selective A Eur J Med Chem134:218-229 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50242120 |
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| n/a |
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| Name | BDBM50242120 |
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| Synonyms: | CHEMBL4059779 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H17F3N6O3 |
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| Mol. Mass. | 458.3933 |
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| SMILES | CCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1cnn(CC#Cc2ccc(OC(F)(F)F)cc2)c1 |
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| Structure | 
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