| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50242683 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1672056 (CHEMBL4022085) |
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| Ki | 0.501187±n/a nM |
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| Citation |  Jiang, L; Beattie, DT; Jacobsen, JR; Kintz, S; Obedencio, GP; Saito, D; Stergiades, I; Vickery, RG; Long, DD Discovery of N-substituted-endo-3-(8-aza-bicyclo[3.2.1]oct-3-yl)-phenol and -phenyl carboxamide series of?-opioid receptor antagonists. Bioorg Med Chem Lett27:2926-2930 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM50242683 |
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| n/a |
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| Name | BDBM50242683 |
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| Synonyms: | CHEMBL4084184 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H31NO |
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| Mol. Mass. | 349.509 |
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| SMILES | [H][C@@]12CC[C@]([H])(CC(C1)c1cccc(O)c1)N2Cc1ccc(cc1)C(C)(C)C |r,@@:7,TLB:9:7:3.2:16| |
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| Structure | 
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