| Reaction Details |
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 | Report a problem with these data |
| Target | Aromatase |
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| Ligand | BDBM50303499 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1672252 |
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| IC50 | >10000±n/a nM |
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| Citation |  Yamaguchi, Y; Nishizono, N; Kobayashi, D; Yoshimura, T; Wada, K; Oda, K Evaluation of synthesized coumarin derivatives on aromatase inhibitory activity. Bioorg Med Chem Lett27:2645-2649 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aromatase |
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| Name: | Aromatase |
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| Synonyms: | ARO1 | Aromatase | CP19A_HUMAN | CYAR | CYP19 | CYP19A1 | CYPXIX | Cytochrome P-450AROM | Cytochrome P450 19A1 | Cytochrome P450 2C19 | Cytochrome P450-C19 (CYP19) | Estrogen synthetase | FL cytokine receptor precursor | P-450AROM |
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| Type: | Enzyme |
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| Mol. Mass.: | 57888.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11511 |
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| Residue: | 503 |
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| Sequence: | MVLEMLNPIHYNITSIVPEAMPAATMPVLLLTGLFLLVWNYEGTSSIPGPGYCMGIGPLI
SHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKL
GLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTN
ESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQGYFDAWQALLIKPDIFFKISWL
YKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCI
LEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFI
YESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEFFPKPNEFTLENFAK
NVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLH
PDETKNMLEMIFTPRNSDRCLEH
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| BDBM50303499 |
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| n/a |
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| Name | BDBM50303499 |
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| Synonyms: | 7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin | 7-methoxy-2H-1-benzopyran-2-one | Ayapanin | CHEMBL49732 | Herniarin | Herniarine | Methylumbelliferone |
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| Type | Small organic molecule |
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| Emp. Form. | C10H8O3 |
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| Mol. Mass. | 176.1687 |
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| SMILES | COc1ccc2ccc(=O)oc2c1 |
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| Structure | 
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