| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
|---|
| Ligand | BDBM50163867 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1673909 (CHEMBL4023938) |
|---|
| Kd | 3.9±n/a nM |
|---|
| Citation |  Linkuvien?, V; Talibov, VO; Danielson, UH; Matulis, D Introduction of Intrinsic Kinetics of Protein-Ligand Interactions and Their Implications for Drug Design. J Med Chem61:2292-2302 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 7 |
|---|
| Name: | Carbonic anhydrase 7 |
|---|
| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29664.11 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Human cloned isozyme. |
|---|
| Residue: | 264 |
|---|
| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
|
|
|
|---|
| BDBM50163867 |
|---|
| n/a |
|---|
| Name | BDBM50163867 |
|---|
| Synonyms: | CHEMBL2443189 | carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 9 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H11N3O3S2 |
|---|
| Mol. Mass. | 309.364 |
|---|
| SMILES | NS(=O)(=O)c1cccc(c1)C(=O)CSc1ncccn1 |
|---|
| Structure | 
|
|---|
Search and Browse
