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TargetSerotonin 1d (5-HT1d) receptor
LigandBDBM30707
Substrate/Competitorn/a
Meas. Tech.ChEBML_1658
IC50 49±n/a nM
Citation Macor JEBlake JFox CBJohnson CKoe BKLebel LAMorrone JMRyan KSchmidt AWSchulz DW Synthesis and serotonergic pharmacology of the enantiomers of 3-[(N-methylpyrrolidin-2-yl)methyl]-5-methoxy-1H-indole: discovery of stereogenic differentiation in the aminoethyl side chain of the neurotransmitter serotonin. J Med Chem 35:4503-5 (1992) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Serotonin 1d (5-HT1d) receptor
Name:Serotonin 1d (5-HT1d) receptor
Synonyms:5-HT1D | 5-hydroxytryptamine receptor 1D | HTR1D
Type:Enzyme Catalytic Domain
Mol. Mass.:41780.38
Organism:GUINEA PIG
Description:5-HT1D HTR1D GUINEA PIG::Q60484
Residue:376
Sequence:
MSPPNQSEEGLPQEASNRSLNATETPGDWDPGLLQALKVSLVVVLSIITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAGAMIAAVWVISICISIPPLFWRQAQ
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYSRIYRAARSRILNPPSLSGKRFT
TAHLITGSAGSSLCSLNPSLHEGHMHPGSPLFFNHVRIKLADSVLERKRISAARERKATK
TLGIILGAFIVCWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNE
DFRQAFQKVVHFRKAS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM30707
n/a
NameBDBM30707
Synonyms:2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamine | 2-(5-methoxy-1H-indol-3-yl)-N,N-dimethylethanamine | 2-(5-methoxy-1H-indol-3-yl)ethyl-dimethyl-amine | 3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7257 | MLS000069438 | Methoxydimethyltryptamines | SMR000059066 | cid_1832
TypeSmall organic molecule
Emp. Form.C13H18N2O
Mol. Mass.218.2948
SMILESCOc1ccc2[nH]cc(CCN(C)C)c2c1
Structure
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