| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1D |
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| Ligand | BDBM50081702 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1658 |
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| IC50 | 420±n/a nM |
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| Citation |  Macor, JE; Blake, J; Fox, CB; Johnson, C; Koe, BK; Lebel, LA; Morrone, JM; Ryan, K; Schmidt, AW; Schulz, DW Synthesis and serotonergic pharmacology of the enantiomers of 3-[(N-methylpyrrolidin-2-yl)methyl]-5-methoxy-1H-indole: discovery of stereogenic differentiation in the aminoethyl side chain of the neurotransmitter serotonin. J Med Chem35:4503-5 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1D |
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| Name: | 5-hydroxytryptamine receptor 1D |
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| Synonyms: | 5-HT1D | 5-hydroxytryptamine receptor 1D | 5HT1D_CAVPO | HTR1D | Serotonin 1d (5-HT1d) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41780.38 |
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| Organism: | GUINEA PIG |
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| Description: | 5-HT1D HTR1D GUINEA PIG::Q60484 |
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| Residue: | 376 |
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| Sequence: | MSPPNQSEEGLPQEASNRSLNATETPGDWDPGLLQALKVSLVVVLSIITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAGAMIAAVWVISICISIPPLFWRQAQ
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYSRIYRAARSRILNPPSLSGKRFT
TAHLITGSAGSSLCSLNPSLHEGHMHPGSPLFFNHVRIKLADSVLERKRISAARERKATK
TLGIILGAFIVCWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNE
DFRQAFQKVVHFRKAS
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| BDBM50081702 |
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| n/a |
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| Name | BDBM50081702 |
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| Synonyms: | 5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole | CHEMBL133939 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H20N2O |
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| Mol. Mass. | 244.3321 |
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| SMILES | COc1ccc2[nH]cc(C[C@@H]3CCCN3C)c2c1 |
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| Structure | 
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