| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Catechol O-methyltransferase |
|---|
| Ligand | BDBM50004044 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_47060 (CHEMBL661101) |
|---|
| Ki | 13500±n/a nM |
|---|
| Citation |  Pérez, RA; Fernández-Alvarez, E; Nieto, O; Piedrafita, FJ Dihydroxynitrobenzaldehydes and hydroxymethoxynitrobenzaldehydes: synthesis and biological activity as catechol-O-methyltransferase inhibitors. J Med Chem35:4584-8 (1993) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Catechol O-methyltransferase |
|---|
| Name: | Catechol O-methyltransferase |
|---|
| Synonyms: | COMT | COMT_PIG |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 20586.58 |
|---|
| Organism: | Sus scrofa |
|---|
| Description: | ChEMBL_105412 |
|---|
| Residue: | 186 |
|---|
| Sequence: | KERAMHVGRKKGQIVDTVVQEQRPSVLLELGAYCGYSAVRMARLLLPSARLLTIELNPDN
AAIAQQVVDFAGLQDRVTVVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLE
ECGLLRKGTVLLADNVICPGAPDFLAHVRGCGRFECTHFSSYLEYSQMVDGLEKAVYKGP
GSPAQP
|
|
|
|---|
| BDBM50004044 |
|---|
| n/a |
|---|
| Name | BDBM50004044 |
|---|
| Synonyms: | 3-Hydroxy-4-methoxy-5-nitro-benzaldehyde | CHEMBL89320 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C8H7NO5 |
|---|
| Mol. Mass. | 197.1449 |
|---|
| SMILES | COc1c(O)cc(C=O)cc1[N+]([O-])=O |
|---|
| Structure | 
|
|---|
Search and Browse
