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TargetPhospholipase A2, major isoenzyme
LigandBDBM50004496
Substrate/Competitorn/a
Meas. Tech.ChEBML_156346
IC50 10000±n/a nM
Citation Bennion, CConnolly, SGensmantel, NPHallam, CJackson, CGPrimrose, WURoberts, GCRobinson, DHSlaich, PK Design and synthesis of some substrate analogue inhibitors of phospholipase A2 and investigations by NMR and molecular modeling into the binding interactions in the enzyme-inhibitor complex. J Med Chem35:2939-51 (1992) [PubMed]
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Phospholipase A2, major isoenzyme
Name:Phospholipase A2, major isoenzyme
Synonyms:Group IB phospholipase A2 | PA21B_PIG | PLA2G1B | Phosphatidylcholine 2-acylhydrolase | Phospholipase A2
Type:Hydrolase; monomer or homodimer
Mol. Mass.:16279.83
Organism:Sus scrofa (pig)
Description:Purchased from Sigma.
Residue:146
Sequence:
MKFLVLAVLLTVGAAQEGISSRALWQFRSMIKCAIPGSHPLMDFNNYGCYCGLGGSGTPV
DELDRCCETHDNCYRDAKNLDSCKFLVDNPYTESYSYSCSNTEITCNSKNNACEAFICNC
DRNAAICFSKAPYNKEHKNLDTKKYC
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BDBM50004496
n/a
NameBDBM50004496
Synonyms:CHEMBL318193 | Phosphoric acid mono-(2-hexadecanoylamino-4-methyl-pentyl) ester
TypeSmall organic molecule
Emp. Form.C22H46NO5P
Mol. Mass.435.5781
SMILESCCCCCCCCCCCCCCCC(=O)N[C@@H](COP(O)(O)=O)CC(C)C
Structure
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