| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM50004653 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_138550 |
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| IC50 | 670.0±n/a nM |
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| Citation |  Valli, MJ; Tang, Y; Kosh, JW; Chapman, JM; Sowell, JW Synthesis and cholinergic properties of N-aryl-2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethylamino analogs of ranitidine. J Med Chem35:3141-7 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_MOUSE | Cholinergic receptor, muscarinic 1, CNS | Cholinergic, muscarinic | Chrm-1 | Chrm1 | Muscarinic acetylcholine receptor | Muscarinic acetylcholine receptor M1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51400.50 |
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| Organism: | Mus musculus |
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| Description: | Cholinergic, muscarinic 0 0::Q52KQ0 |
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| Residue: | 460 |
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| Sequence: | MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM50004653 |
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| n/a |
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| Name | BDBM50004653 |
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| Synonyms: | CHEMBL106348 | N-(2-Dimethylamino-ethyl)-N'-[2-(5-dimethylaminomethyl-furan-2-ylmethylsulfanyl)-ethyl]-4,6-dinitro-benzene-1,3-diamine |
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| Type | Small organic molecule |
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| Emp. Form. | C20H30N6O5S |
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| Mol. Mass. | 466.554 |
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| SMILES | CN(C)CCNc1cc(NCCSCc2ccc(CN(C)C)o2)c(cc1[N+]([O-])=O)[N+]([O-])=O |
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| Structure | 
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