| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50247453 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1677774 (CHEMBL4027917) |
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| Ki | 8680±n/a nM |
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| Citation |  Petrelli, R; Scortichini, M; Belardo, C; Boccella, S; Luongo, L; Capone, F; Kachler, S; Vita, P; Del Bello, F; Maione, S; Lavecchia, A; Klotz, KN; Cappellacci, L Structure-Based Design, Synthesis, and In Vivo Antinociceptive Effects of Selective A J Med Chem61:305-318 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50247453 |
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| n/a |
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| Name | BDBM50247453 |
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| Synonyms: | CHEMBL4103712 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H17Cl2N5O4 |
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| Mol. Mass. | 390.222 |
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| SMILES | O[C@@H]1[C@@H](CCl)O[C@H]([C@@H]1O)n1cnc2c(N[C@@H]3CCOC3)nc(Cl)nc12 |r| |
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| Structure | 
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