| Reaction Details |
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 | Report a problem with these data |
| Target | Nicotinamide N-methyltransferase |
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| Ligand | BDBM50247635 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1678256 (CHEMBL4028399) |
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| Kd | 42800±n/a nM |
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| Citation |  Babault, N; Allali-Hassani, A; Li, F; Fan, J; Yue, A; Ju, K; Liu, F; Vedadi, M; Liu, J; Jin, J Discovery of Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT). J Med Chem61:1541-1551 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Nicotinamide N-methyltransferase |
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| Name: | Nicotinamide N-methyltransferase |
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| Synonyms: | NNMT | NNMT_HUMAN | Nicotinamide N-methyltransferase | Nicotinamide N-methyltransferase (NNMT) |
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| Type: | Protein |
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| Mol. Mass.: | 29571.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 264 |
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| Sequence: | MESGFTSKDTYLSHFNPRDYLEKYYKFGSRHSAESQILKHLLKNLFKIFCLDGVKGDLLI
DIGSGPTIYQLLSACESFKEIVVTDYSDQNLQELEKWLKKEPEAFDWSPVVTYVCDLEGN
RVKGPEKEEKLRQAVKQVLKCDVTQSQPLGAVPLPPADCVLSTLCLDAACPDLPTYCRAL
RNLGSLLKPGGFLVIMDALKSSYYMIGEQKFSSLPLGREAVEAAVKEAGYTIEWFEVISQ
SYSSTMANNEGLFSLVARKLSRPL
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| BDBM50247635 |
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| n/a |
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| Name | BDBM50247635 |
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| Synonyms: | CHEMBL4100002 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H30N8O6 |
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| Mol. Mass. | 514.5343 |
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| SMILES | N[C@@H](CCN(CCc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| |
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| Structure | 
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