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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Bile salt export pump | ||
| Ligand | BDBM50355610 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1678644 (CHEMBL4028921) | ||
| IC50 | >133000±n/a nM | ||
| Citation |  Morgan, RE; van Staden, CJ; Chen, Y; Kalyanaraman, N; Kalanzi, J; Dunn, RT; Afshari, CA; Hamadeh, HK A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicol Sci136:216-41 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Bile salt export pump | |||
| Name: | Bile salt export pump | ||
| Synonyms: | ABCB11 | ABCBB_HUMAN | ATP-binding cassette sub-family B member 11 | BSEP | Bile Salt Export Pump, BSEP | Bile salt export pump | Bile salt export pump (BSEP) | ||
| Type: | Protein | ||
| Mol. Mass.: | 146405.49 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O95342 | ||
| Residue: | 1321 | ||
| Sequence: |
| ||
| BDBM50355610 | |||
| n/a | |||
| Name | BDBM50355610 | ||
| Synonyms: | CHEMBL1237108 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H30NO3 | ||
| Mol. Mass. | 332.4566 | ||
| SMILES | CC(C)[N+]1(C)C2CCC1CC(C2)OC(=O)C(CO)c1ccccc1 |TLB:4:3:6.7:11.9.10,1:3:6.7:11.9.10,(10.09,.76,;9.35,2.05,;7.85,2.05,;10.09,3.35,;11.39,2.6,;10.09,4.89,;10.86,3.55,;10.3,2.58,;8.76,2.58,;7.43,3.35,;7.43,4.89,;8.76,5.66,;6.09,5.66,;6.09,7.2,;7.43,7.97,;4.76,7.97,;4.76,9.51,;3.43,10.28,;3.43,7.2,;3.43,5.66,;2.09,4.89,;.76,5.66,;.76,7.2,;2.09,7.97,)| | ||
| Structure | 
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