Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetGrowth hormone-releasing hormone receptor
LigandBDBM50004976
Substrate/Competitorn/a
Meas. Tech.ChEBML_72520
IC50 1.9±n/a nM
Citation Gaudreau, PBoulanger, LAbribat, T Affinity of human growth hormone-releasing factor (1-29)NH2 analogues for GRF binding sites in rat adenopituitary. J Med Chem35:1864-9 (1992) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Growth hormone-releasing hormone receptor
Name:Growth hormone-releasing hormone receptor
Synonyms:GHRH receptor | GHRHR_RAT | GRF receptor | Ghrhr | Grfr
Type:PROTEIN
Mol. Mass.:51523.38
Organism:Rattus norvegicus
Description:ChEMBL_193173
Residue:464
Sequence:
MDSLLWATWVLCLLNLWGVALGHLHLECDFITQLRDDELACLQAAEGTNNSSMGCPGTWD
GLLCWPPTGSGQWVSLPCPEFFSHFGSDPGAVKRDCTITGWSDPFPPYPVACPVPLELLT
EEKSYFSTVKIIYTTGHSISIVALCVAIAILVALRRLHCPRNYIHTQLFATFILKASAVF
LKDAAVFQGDSTDHCSMSTILCKVSVAVSHFATMTNFSWLLAEAVYLSCLLASTSPRSKP
AFWWLVLAGWGLPVLCTGTWVGCKLAFEDTACWDLDDSSPYWWIIKGPIVLSVGVNFGLF
LNIICILLRKLGPAQGGLHTRAQYCNYLLPWSCPLPQVPRERTDLGPSSHEITVQESGTR
NCQLPWRLSKSTLLLIPLFGIHYIIFNFLPDSAGLGIRLPLELGLGSFQGFVVAVLYCFL
NQEVRTEISRKWYGHDPELLPARRTCTEWTTPPRSRVKVLTSEC
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50004976
n/a
NameBDBM50004976
Synonyms:CHEMBL385308 | GRF-analogues
TypeSmall organic molecule
Emp. Form.C157H253N49O41S
Mol. Mass.3515.057
SMILESn/a
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: