| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Advanced glycosylation end product-specific receptor |
|---|
| Ligand | BDBM50249567 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1680058 (CHEMBL4030335) |
|---|
| Ki | 230±n/a nM |
|---|
| Citation |  Bongarzone, S; Savickas, V; Luzi, F; Gee, AD Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A Medicinal Chemistry Perspective. J Med Chem60:7213-7232 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Advanced glycosylation end product-specific receptor |
|---|
| Name: | Advanced glycosylation end product-specific receptor |
|---|
| Synonyms: | AGER | RAGE | RAGE_HUMAN | Receptor for advanced glycosylation end products |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 42800.11 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1339877 |
|---|
| Residue: | 404 |
|---|
| Sequence: | MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA
WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI
PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH
PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL
VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYS
CVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGV
ILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP
|
|
|
|---|
| BDBM50249567 |
|---|
| n/a |
|---|
| Name | BDBM50249567 |
|---|
| Synonyms: | CHEMBL4075936 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H22ClNO |
|---|
| Mol. Mass. | 327.848 |
|---|
| SMILES | Clc1ccc(cc1)C(=O)N(Cc1ccccc1)C1CCCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
