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TargetC-X-C chemokine receptor type 7 (CXCR7)
LigandBDBM50250378
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1681650
Ki 79±n/a nM
Citation Boehm MBeaumont KJones RKalgutkar ASZhang LAtkinson KBai GBrown JAEng HGoetz GHHolder BRKhunte BLazzaro SLimberakis CRyu SShapiro MJTylaska LYan JTurner RLeung SSFRamaseshan MPrice DALiras SJacobson MPEarp DJLokey RSMathiowetz AMMenhaji-Klotz E Discovery of Potent and Orally Bioavailable Macrocyclic Peptide-Peptoid Hybrid CXCR7 Modulators. J Med Chem 60:9653-9663 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
C-X-C chemokine receptor type 7 (CXCR7)
Name:C-X-C chemokine receptor type 7 (CXCR7)
Synonyms:C-X-C chemokine receptor type 7 | CMKOR1 | CXC-R7 | CXCR-7 | CXCR7 | Chemokine orphan receptor 1 | G-protein coupled receptor 159 | G-protein coupled receptor RDC1 homolog | GPR159 | RDC-1 | RDC1
Type:Enzyme
Mol. Mass.:41498.84
Organism:Homo sapiens (Human)
Description:P25106
Residue:362
Sequence:
MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMI
ANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVT
HLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDT
YYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAIS
ASSDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVT
QCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQS
TK
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BDBM50250378
n/a
NameBDBM50250378
Synonyms:CHEMBL4096619
TypeSmall organic molecule
Emp. Form.C54H61N7O6
Mol. Mass.904.1054
SMILESO=C1CN(CCCc2ccccc2)C(=O)[C@H]2CCCN2C(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](CCc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCCc2ccccc2)N1 |r|
Structure
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